👩🔬📢 LongTREC in action: A Young Biology Olympian Explores the SQANTI-verse
Once again this year, Tianyuan Liu and Fabian Jetzinger, Doctoral Candidates at I2SysBio and BioBam respectively, welcomed a participant in the Spanish National Biology Olympiad 🧬🇪🇸 to the Genomics of Gene Expression (GGE) Lab at I2SysBio (CSIC-UV). In early July 2025, Roc Martin visited the lab to learn about long reads and transcriptomics. Tianyuan and […]
🔔 Planning a Conference Trip? Here’s How to Make It More Sustainable!
♻️ Tips for Greener Conference Travel: […]
👩🔬📢 Fascination of Plants Day
On Fascination of Plants Day, Nadja Nolte, Doctoral Candidate at the National Institute of Biology in Slovenia, took part in an interactive activity introducing 11-year-old students to the basics of sequencing and BLAST searches. A challenging topic? Absolutely! Impossible? Not at all, especially when you mix LEGO + curious students + highly motivated researchers eager […]
👨🔬🌍 Research Mobility Experience – Fabio at Genoscope
Scalable Genome Annotation at CEA-Genoscope From March 10 to May 2, 2025, Fabio Zanarello, LongTREC Doctoral Candidate at the Centre for Genomic Regulation (CRG), had the opportunity to carry out a research secondment at CEA-Genoscope, supervised by France Denoeud and Jean-Marc Aury. This secondment offered valuable growth, both in scientific expertise and personal development. My […]
🏆 Eva Novoa awarded with the 2024 National Young Talent Research Award
Recently, we had the pleasure of sitting down with Dr.Eva Maria Novoa, one of our LongTREC project supervisors, whose groundbreaking work in RNA biology, specifically in the emerging field of epitranscriptomics, has been recognised with the 2024 National Young Talent Research Award by the Fundació Catalana per a la Recerca i la Innovació. This prestigious […]
LongTREC presents: Transcriptomics in the era of long-read sequencing
LongTREC presents: Transcriptomics in the era of long-read sequencing Carolina Monzó, Tianyuan Liu, Ana Conesa Our genes work by producing RNA copies, called transcripts, that carry the instructions to make proteins. A single gene can produce many different versions of these transcripts, known as isoforms, by combining its pieces in different ways. Studying them is […]
LongTREC presents: Toward the use of nanopore RNA sequencing technologies in the clinic: challenges and opportunities
LongTREC presents: Toward the use of nanopore RNA sequencing technologies in the clinic: challenges and opportunities Xanthi-Lida Katopodi, Oguzhan Begik, Eva Maria Novoa RNA molecules are increasingly seen as potential clinical biomarkers: signals in our body that can help detect or monitor disease. Today, RNA is usually measured with short-read sequencing or PCR tests. These […]
LongTREC presents: Quality assessment of long read data in multisample lrRNA-seq experiments using SQANTI-reads
LongTREC presents: Quality assessment of long read data in multisample lrRNA-seq experiments using SQANTI-reads Netanya Keil, Carolina Monzó, Lauren McIntyre, Ana Conesa Long-read RNA sequencing lets scientists read entire RNA molecules and discover which versions of each gene’s transcripts are present. But, as in any experiment, data quality can vary between samples, and poor samples […]
LongTREC presents: IsoTools 2.0: Software for Comprehensive Analysis of Long-read Transcriptome Sequencing Data
LongTREC presents: IsoTools 2.0: Software for Comprehensive Analysis of Long-read Transcriptome Sequencing Data Yalan Bi, Tom Lukas Lankenau, Matthias Lienhard, Ralf Herwig A single gene can produce several different RNA versions, or isoforms, by joining its pieces in different combinations, a process called alternative splicing. Long-read transcriptome sequencing reads each RNA molecule in one go, […]
👨🔬🌍 Research Mobility Experience – Sami at CSIC
Memory-Efficient Isoform Clustering at CSIC From December 3, 2024 to February 24, 2025, Mahmud Sami Aydin, LongTREC Doctoral Candidate at Stockholm University, had the opportunity to carry out a research secondment at CSIC, supervised by Ana Conesa. This secondment offered valuable growth, both in scientific expertise and personal development. My goal? Exploring mapping-friendly compression methods […]
👨🔬🌍 Research Mobility Experience – Tianyuan at IIT
Hia5 Chromatin Methylation at the Istituto Italiano di Tecnologia From December 2, 2024 to February 22, 2025, Tianyuan Liu, LongTREC Doctoral Candidate at the Institute for Integrative Systems Biology (CSIC-UV) in Valencia, had the opportunity to carry out a research secondment at the Istituto Italiano di Tecnologia, supervised by Francesco Nicassio. This secondment offered valuable […]
🧬 Unlocking Long-Read Transcriptomics: Reference-Free Analysis of Long-Read RNA Sequencing for Non-Model Species
Reference-Free Analysis of Long-Read RNA Sequencing for Non-Model Species Fabian Jetzinger, Doctoral Candidate at BioBam Bioinformatics, explains how to characterize RNA isoforms from long-read data without a reference genome, using the isON-pipeline in OmicsBox. Isoform identification tools such as FLAIR and IsoQuant work well when a reliable reference genome and transcriptome are available, but offer […]